Determination of <i>NAT2</i> Genotypes in a Cohort of Patients with Suspected TB in the State of Rio de Janeiro

• Main Authors: Cecília Alvim Dutra (Author), Raquel Lima de Figueiredo Teixeira (Author), Márcia Quinhones Pires Lopes (Author), Victória de Moraes Silva (Author), Philip Noel Suffys (Author), Ricardo de Souza Carvalho (Author), Adriana Rezende Moreira (Author), Adalberto Rezende Santos (Author), Afrânio Lineu Kritski (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The human N-acetyltransferase 2 enzyme, encoded by the <i>NAT2</i> gene, plays an important role in the metabolism of isoniazid, the main drug used to treat tuberculosis. The interindividual variation in the response of patients to drug treatment for tuberculosis may be responsible for t...