Role of Hepatocyte Transporters in Drug-Induced Liver Injury (DILI)-In Vitro Testing

Bile acids and bile salts (BA/BS) are substrates of both influx and efflux transporters on hepatocytes. Canalicular efflux transporters, such as BSEP and MRP2, are crucial for the removal of BA/BS to the bile. Basolateral influx transporters, such as NTCP, OATP1B1/1B3, and OSTα/β, cooperate with can...

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Main Authors: Péter Tátrai (Author), Franciska Erdő (Author), Péter Krajcsi (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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