A ROCK1 Inhibitior Fasudil Alleviates Cardiomyocyte Apoptosis in Diabetic Cardiomyopathy by Inhibiting Mitochondrial Fission in a Type 2 Diabetes Mouse Model

• Главные авторы: Xinhui Fan (Автор), Xiaoxing Li (Автор), Huiruo Liu (Автор), Feng Xu (Автор), Xiaoping Ji (Автор), Yuguo Chen (Автор), Chuanbao Li (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Предметы: article
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Diabetes mellitus (DM) often involves cardiovascular complications; however, treatment regimens are limited. ROCK1 (rho-associated coiled-coil containing protein kinase 1) serves as a pathological factor in several diabetic complications. Herein, we aimed to explore the effect of Fasudil (a ROCK1 in...