A ROCK1 Inhibitior Fasudil Alleviates Cardiomyocyte Apoptosis in Diabetic Cardiomyopathy by Inhibiting Mitochondrial Fission in a Type 2 Diabetes Mouse Model

• Hlavní autoři: Xinhui Fan (Autor), Xiaoxing Li (Autor), Huiruo Liu (Autor), Feng Xu (Autor), Xiaoping Ji (Autor), Yuguo Chen (Autor), Chuanbao Li (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Diabetes mellitus (DM) often involves cardiovascular complications; however, treatment regimens are limited. ROCK1 (rho-associated coiled-coil containing protein kinase 1) serves as a pathological factor in several diabetic complications. Herein, we aimed to explore the effect of Fasudil (a ROCK1 in...