Do Mixtures of Beads with Different Sizes Improve Wet Stirred Media Milling of Drug Suspensions?

• Main Authors: Gulenay Guner (Author), Mirsad Mehaj (Author), Natasha Seetharaman (Author), Sherif Elashri (Author), Helen F. Yao (Author), Donald J. Clancy (Author), Ecevit Bilgili (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The impacts of bead sizes and bead mixtures on breakage kinetics, the number of milling cycles applied to prevent overheating, and power consumption during the nanomilling of drug (griseofulvin) suspensions were investigated from both an experimental and theoretical perspective. Narrowly sized zirco...