Protective effect of yacon leaves extract (Smallanthus sonchifolius(Poepp.) H. Rob) through antifibrosis, anti-inflammatory, and antioxidant mechanisms toward diabetic nephropathy

• Main Authors: Wahyu Widowati (Author), Rita Tjokropranoto (Author), Philips Onggowidjaja (Author), Hanna Sari Widya Kusuma (Author), Cahyaning Riski Wijayanti (Author), Meganita Marthania (Author), Afif Yati (Author), Rizal Rizal (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and purpose: Diabetic nephropathy (DN) is a chronic kidney failure, which may lead to fatality. Mesangial cell proliferation, renal inflammation, stress oxidative, and fibrosis are involved in DN progression. Yacon leaves (Smallanthus sonchifolius (Poepp.) H. Rob.) contains large amounts...