Analysis of the circRNA and T-UCR populations identifies convergent pathways in mouse and human models of Rett syndrome

• Main Authors: Edilene Siqueira (Author), Aida Obiols-Guardia (Author), Olga C. Jorge-Torres (Author), Cristina Oliveira-Mateos (Author), Marta Soler (Author), Deepthi Ramesh-Kumar (Author), Fernando Setién (Author), Daniëlle van Rossum (Author), Ainhoa Pascual-Alonso (Author), Clara Xiol (Author), Cristina Ivan (Author), Masayoshi Shimizu (Author), Judith Armstrong (Author), George A. Calin (Author), R. Jeroen Pasterkamp (Author), Manel Esteller (Author), Sonia Guil (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Noncoding RNAs play regulatory roles in physiopathology, but their involvement in neurodevelopmental diseases is poorly understood. Rett syndrome is a severe, progressive neurodevelopmental disorder linked to loss-of-function mutations of the MeCP2 gene for which no cure is yet available. Analysis o...