Autophagy in kidney transplants of sirolimus treated recipients

• Main Authors: Sagar Bhayana (Author), Arpita Baisantry (Author), Thomas D. Kraemer (Author), Christoph Wrede (Author), Jan Hegermann (Author), Jan-Hinrich Bräsen (Author), Clemens Bockmeyer (Author), Jan Ulrich Becker (Author), Matthias Ochs (Author), Wilfried Gwinner (Author), Hermann Haller (Author), Anette Melk (Author), Roland Schmitt (Author)
• Format: Book
• Published: Society of Diabetic Nephropathy Prevention, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Mammalian target of rapamycin (mTOR) inhibitors are increasingly used as immunosuppressive agents in kidney transplantation. In the experimental setting it has been shown that mTOR inhibitors promote autophagy, but the concept that this might also occur in transplant patients has not bee...