Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size

• Main Authors: Abishek Wadhwa (Author), Thomas R. Bobak (Author), Lennart Bohrmann (Author), Reka Geczy (Author), Sathiya Sekar (Author), Gowtham Sathyanarayanan (Author), Jörg P. Kutter (Author), Henrik Franzyk (Author), Camilla Foged (Author), Katayoun Saatchi (Author), Urs O. Häfeli (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanomedicines based on nanoparticles rely both on the potency of the drug as well as the efficiency of the delivery system, for which particle size plays a crucial role. For the intracellular delivery of small interference RNA (siRNA), lipid-polymer nanoparticle (LPN) hybrid systems constitute a saf...