Discovery of New 3-(Benzo[<i>b</i>]Thiophen-2-yl)Pyrrolidine-2,5-Dione Derivatives as Potent Antiseizure and Antinociceptive Agents-In Vitro and In Vivo Evaluation

• Main Authors: Anna Rapacz (Author), Marcin Jakubiec (Author), Michał Abram (Author), Jakub Jasiński (Author), Karolina Chrzan (Author), Małgorzata Góra (Author), Anna Dziubina (Author), Katarzyna Wójcik-Pszczoła (Author), Paulina Koczurkiewicz-Adamczyk (Author), Katarzyna Ciepiela (Author), Elżbieta Pękala (Author), Jolanta Obniska (Author), Krzysztof Kamiński (Author)
• Format: Book
• Published: MDPI AG, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background/Objectives</b>: To address the unmet clinical needs in the treatment of epilepsy and pain, the continued development of more effective and safer anticonvulsants and analgesics is still necessary. Therefore, herein we report synthesis and antiseizure/antinociceptive evaluati...