Identification of novel CDK2 inhibitors by a multistage virtual screening method based on SVM, pharmacophore and docking model

Cyclin-dependent kinase 2 (CDK2) is the family of Ser/Thr protein kinases that has emerged as a highly selective with low toxic cancer therapy target. A multistage virtual screening method combined by SVM, protein-ligand interaction fingerprints (PLIF) pharmacophore and docking was utilised for scre...

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Hoofdauteurs: Jing-Wei Liang (Auteur), Ming-Yang Wang (Auteur), Shan Wang (Auteur), Shi-Long Li (Auteur), Wan-Qiu Li (Auteur), Fan-Hao Meng (Auteur)
Formaat: Boek
Gepubliceerd in: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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