Identification of novel CDK2 inhibitors by a multistage virtual screening method based on SVM, pharmacophore and docking model
Cyclin-dependent kinase 2 (CDK2) is the family of Ser/Thr protein kinases that has emerged as a highly selective with low toxic cancer therapy target. A multistage virtual screening method combined by SVM, protein-ligand interaction fingerprints (PLIF) pharmacophore and docking was utilised for scre...
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Formaat: | Boek |
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Taylor & Francis Group,
2020-01-01T00:00:00Z.
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Internet
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A1234.567 |
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Kopie 1 | Beschikbaar |