Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug-Drug Interactions of Phenytoin

• Main Authors: Leyanis Rodriguez-Vera (Author), Xuefen Yin (Author), Mohammed Almoslem (Author), Karolin Romahn (Author), Brian Cicali (Author), Viera Lukacova (Author), Rodrigo Cristofoletti (Author), Stephan Schmidt (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Regulatory agencies worldwide expect that clinical pharmacokinetic drug-drug interactions (DDIs) between an investigational new drug and other drugs should be conducted during drug development as part of an adequate assessment of the drug's safety and efficacy. However, it is neither time nor c...