Harmine Has Nephroprotective Effect Against Methotrexate-Induced Injury in Mice via Inhibition of Oxidative Stress

Background and objectives: Despite clinical use, the efficacy of methotrexate is often limited by some adverse effects, mainly nephrotoxicity. The most common mechanism of methotrexate-induced kidney damages is oxidative stress. Harmine as a plant-derived compound has antioxidant and anti-inflammato...

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Main Authors: Cyrus Jalili (Author), Sara Darakhshan (Author), Nasim Akhshi (Author), Amir Abdolmaleki (Author), Abdolnasir Abdi (Author), Ali Ghanbari* (Author)
Format: Book
Published: Iranian Society of Pharmacognosy, 2021-10-01T00:00:00Z.
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