Ionic Liquid 1-Octyl-3-Methylimidazolium (M8OI) Is Mono-Oxygenated by CYP3A4 and CYP3A5 in Adult Human Liver

• Үндсэн зохиолчид: Alistair C. Leitch (Зохиогч), Tarek M. Abdelghany (Зохиогч), Alex Charlton (Зохиогч), Martin Cooke (Зохиогч), Matthew C. Wright (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2024-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Environmental sampling around a landfill site in the UK previously identified the methylimidazolium ionic liquid, 1-octyl-3-methylimidazolium (M8OI), in the soil. More recently, M8OI was shown to be detectable in sera from 5/20 PBC patients and 1/10 controls and to be oxidised on the alkyl chain in...