8-Hydroxy-2'-Deoxyguanosine and 8-Nitroguanine Production and Detection in Blood Serum of Breast Cancer Patients in Response to Postoperative Complementary External Ionizing Irradiation of Normal Tissues

• Główni autorzy: Kosmas E. Verigos (Autor), Sofia Sagredou (Autor), Kyriakos Orfanakos (Autor), Panayiotis Dalezis (Autor), Dimitrios T. Trafalis (Autor)
• Format: Książka
• Wydane: SAGE Publishing, 2020-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

It is widely known that ionizing irradiation is strongly linked to the production of reactive oxygen (ROS) and nitrative species (RNS) through which DNA damage products like 8-hydroxy-2-deoxyguanosine (8-OHdG) and 8-nitroguanine (8-NG) are generated, respectively. In the present study, we aimed to i...