Non-invasive type 2 diabetes risk scores do not identify diabetes when the cause is β-cell failure: The Africans in America study

• Main Authors: Annemarie Wentzel (Author), Arielle C. Patterson (Author), M. Grace Duhuze Karera (Author), Zoe C. Waldman (Author), Blayne R. Schenk (Author), Christopher W. DuBose (Author), Anne E. Sumner (Author), Margrethe F. Horlyck-Romanovsky (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundEmerging data suggests that in sub-Saharan Africa β-cell-failure in the absence of obesity is a frequent cause of type 2 diabetes (diabetes). Traditional diabetes risk scores assume that obesity-linked insulin resistance is the primary cause of diabetes. Hence, it is unknown whether diabet...