Dissolution of theophylline from extended-release tablets under cyclic retrograde peristaltic contractions in the Dynamic Colon Model
The dynamic colon model isa biorelevant in vitro model of the human proximal colon. In vivo, the large intestine mixes its contents using peristaltic waves that propagate both forwards(antegrade) and backwards (retrograde). This work studies the dissolution profile of theophylline from Uniphyllin Co...
Saved in:
Main Authors: | Connor O'Farrell (Author), Konstantinos Stamatopoulos (Author), Mark J. H. Simmons (Author), Hannah Batchelor (Author) |
---|---|
Format: | Book |
Published: |
University of Huddersfield Press,
2022-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Effect of Biorelevant Hydrodynamic Conditions on Drug Dissolution from Extended-Release Tablets in the Dynamic Colon Model
by: Connor O'Farrell, et al.
Published: (2022) -
Use of In Vitro Dynamic Colon Model (DCM) to Inform a Physiologically Based Biopharmaceutic Model (PBBM) to Predict the In Vivo Performance of a Modified-Release Formulation of Theophylline
by: Konstantinos Stamatopoulos, et al.
Published: (2023) -
Luminal Fluid Motion Inside an In Vitro Dissolution Model of the Human Ascending Colon Assessed Using Magnetic Resonance Imaging
by: Connor O'Farrell, et al.
Published: (2021) -
Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model
by: Michael Schütt, et al.
Published: (2022) -
Correction: Schütt et al. Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model. <i>Pharmaceutics</i> 2022, <i>14</i>, 184
by: Michael Schütt, et al.
Published: (2022)