Control of translation elongation in health and disease

• Main Authors: John R. P. Knight (Author), Gavin Garland (Author), Tuija Pöyry (Author), Emma Mead (Author), Nikola Vlahov (Author), Aristeidis Sfakianos (Author), Stefano Grosso (Author), Fabio De- (Author), Giovanna R. Mallucci (Author), Tobias von der Haar (Author), C. Mark Smales (Author), Owen J. Sansom (Author), Anne E. Willis (Author)
• Format: Book
• Published: The Company of Biologists, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Regulation of protein synthesis makes a major contribution to post-transcriptional control pathways. During disease, or under stress, cells initiate processes to reprogramme protein synthesis and thus orchestrate the appropriate cellular response. Recent data show that the elongation stage of protei...