Knockdown of lincRNA PADNA promotes bupivacaine-induced neurotoxicity by miR-194/FBXW7 axis

Abstract Background The aim of the study was to explore the function and mechanism of lincRNA PADNA in bupivacaine-induced neurotoxicity. Methods Mouse DRG neurons were cultured in vitro and treated with bupivacaine to establish a neurotoxicity model. Caspase3 activity, cell viability, and TUNEL ass...

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Main Authors: Fan Yuning (Author), Chen Liang (Author), Wang Tenghuan (Author), Nan Zhenhua (Author), Gong Shengkai (Author)
Format: Book
Published: BMC, 2020-08-01T00:00:00Z.
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