Stimulation of prostanoids and IL-8 production in human gingival fibroblasts by Porphyromonas gingivalis LPS is associated with MEK/ERK signaling

• Main Authors: Yi-Ling Tsai (Author), Mei-Chi Chang (Author), Li-Deh Lin (Author), Chiu-Po Chan (Author), Chen-Ying Wang (Author), Po-Shuan Lin (Author), Jiiang-Huei Jeng (Author)
• Format: Book
• Published: Elsevier, 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Various toxic products are generated by periodontal pathogens. Porphyromonas gingivalis has been found to generate lipopolysaccharide (LPS) that may potentially affect periodontal health. However, the precise effects of P. gingivalis LPS on human gingival fibroblasts (GFs) await...