Unveiling the Influence of a High-Fat Meal on the Pharmacokinetics of Oral Globalagliatin, A Glucokinase Activator, in Healthy Chinese Volunteers

• Main Authors: Maodi Xu (Author), Yaqin Wang (Author), Xiaohu Wang (Author), Zhichen Pu (Author), Ya Liu (Author), Cuilian Jiang (Author), Xiaokun Shen (Author), Hua Sun (Author), Haitang Xie (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Glucokinase (GK) plays a pivotal role in maintaining glucose homeostasis; globalagliatin, a newly developed drug, is a GK activator (GKA). This study constitutes a randomized, open-label, two-cycle, two-crossover, single-dose, phase I clinical trial conducted at a single center...