In vitro membrane binding and protein binding (IAM MB/PB technology) to estimate in vivo distribution: applications in early drug discovery

The drug discovery process can be accelerated by chromatographic profiling of the analogs to model in vivo distribution and the major non-specific binding. A balanced potency and chromatographically determined membrane and protein binding (IAM MB/PB) data enable selecting drug discovery compounds fo...

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Bibliographic Details
Main Authors: Klara Livia Valko (Author), Simon P. Teague (Author), Charles Pidgeon (Author)
Format: Book
Published: International Association of Physical Chemists (IAPC), 2017-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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