In vitro membrane binding and protein binding (IAM MB/PB technology) to estimate in vivo distribution: applications in early drug discovery
The drug discovery process can be accelerated by chromatographic profiling of the analogs to model in vivo distribution and the major non-specific binding. A balanced potency and chromatographically determined membrane and protein binding (IAM MB/PB) data enable selecting drug discovery compounds fo...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
International Association of Physical Chemists (IAPC),
2017-03-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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