Pharmacometrics enhanced Bayesian borrowing approach to improve clinical trial efficiency: Case of empagliflozin in type 2 diabetes

• প্রধান লেখক: Lucie Fayette (লেখক), Martin Oliver Sailer (লেখক), Alejandro Perez‐Pitarch (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2023-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract We report use of a pharmacometrics enhanced Bayesian borrowing (PEBB) approach to leverage historical clinical trial data on a drug product to build models, project the outcome of future clinical trials, and borrow information from these projections to improve the efficiency of future targe...