Pharmacometrics enhanced Bayesian borrowing approach to improve clinical trial efficiency: Case of empagliflozin in type 2 diabetes

Abstract We report use of a pharmacometrics enhanced Bayesian borrowing (PEBB) approach to leverage historical clinical trial data on a drug product to build models, project the outcome of future clinical trials, and borrow information from these projections to improve the efficiency of future targe...

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Main Authors: Lucie Fayette (Author), Martin Oliver Sailer (Author), Alejandro Perez‐Pitarch (Author)
Format: Book
Published: Wiley, 2023-10-01T00:00:00Z.
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