Neutrophils Are Dysregulated in Patients with Hereditary Angioedema Types I and II in a Symptom-Free Period

• Main Authors: Tereza Grymova (Author), Marcela Vlkova (Author), Premysl Soucek (Author), Roman Hakl (Author), Jana Nechvatalova (Author), Peter Slanina (Author), Julie Stichova (Author), Jiri Litzman (Author), Tomas Freiberger (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neutrophils impact on processes preceding the formation of bradykinin, a major swelling mediator in hereditary angioedema (HAE), yet their potential role in HAE pathogenesis has not been sufficiently studied. We assessed the relative mRNA expression of 10 genes related to neutrophil activation using...