Translational PBPK Modeling of the Protein Therapeutic and CD95L Inhibitor Asunercept to Develop Dose Recommendations for Its First Use in Pediatric Glioblastoma Patients

The protein therapeutic and CD95L inhibitor asunercept is currently under clinical investigation for the treatment of glioblastoma and myelodysplastic syndrome. The purpose of this study was to predict the asunercept pharmacokinetics in children and to give dose recommendations for its first use in...

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Bibliographic Details
Main Authors: Nina Hanke (Author), Claudia Kunz (Author), Meinolf Thiemann (Author), Harald Fricke (Author), Thorsten Lehr (Author)
Format: Book
Published: MDPI AG, 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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