Trichosanthin-induced autophagy in gastric cancer cell MKN-45 is dependent on reactive oxygen species (ROS) and NF-κB/p53 pathway

• Hoofdauteurs: Bin Wei (Auteur), Qiaoying Huang (Auteur), Shunrong Huang (Auteur), Wei Mai (Auteur), Xiaogang Zhong (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2016-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Trichosanthin (TCS), isolated from the root tuber of Trichosanthes kirilowii tubers in the Cucurbitaceae family, owns a great deal of biological and pharmacological activities including anti-virus and anti-tumor. TCS has been reported to induce cell apoptosis of a diversity of cancers, including cer...