Trichosanthin-induced autophagy in gastric cancer cell MKN-45 is dependent on reactive oxygen species (ROS) and NF-κB/p53 pathway

• Main Authors: Bin Wei (Author), Qiaoying Huang (Author), Shunrong Huang (Author), Wei Mai (Author), Xiaogang Zhong (Author)
• Format: Book
• Published: Elsevier, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trichosanthin (TCS), isolated from the root tuber of Trichosanthes kirilowii tubers in the Cucurbitaceae family, owns a great deal of biological and pharmacological activities including anti-virus and anti-tumor. TCS has been reported to induce cell apoptosis of a diversity of cancers, including cer...