Sporothrix globosa melanin regulates autophagy via the TLR2 signaling pathway in THP-1 macrophages.

• Main Authors: Mengqi Guan (Author), Lei Yao (Author), Yu Zhen (Author), Yang Song (Author), Xiaobo Liu (Author), Yuanyuan Liu (Author), Ruili Chen (Author), Yan Cui (Author), Shanshan Li (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Melanin, an important virulence factor of pathogenic fungi, has been shown to suppress host immune responses in multiple ways. Autophagy is a vital cellular mechanism underlying the host's innate immunity against microbial infections. However, the potential influence of melanin on autophagy has...