Darovasertib, a novel treatment for metastatic uveal melanoma

• Main Authors: Lei Cao (Author), Shuzhen Chen (Author), Rainie Sun (Author), Charles R. Ashby (Author), Liuya Wei (Author), Zoufang Huang (Author), Zhe-Sheng Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The FDA granted orphan drug designation to darovasertib, a first-in-class oral, small molecular inhibitor of protein kinase C (PKC), for the treatment of uveal melanoma, on 2 May 2022. Primary uveal melanoma has a high risk of progressing to metastatic uveal melanoma, with a poor prognosis. The acti...