Simulating drug penetration during hyperthermic intraperitoneal chemotherapy

• Main Authors: Daan R. Löke (Author), Roxan F. C. P. A. Helderman (Author), Nicolaas A. P. Franken (Author), Arlene L. Oei (Author), Pieter J. Tanis (Author), Johannes Crezee (Author), H. Petra Kok (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyperthermic intraperitoneal chemotherapy (HIPEC) is administered to treat residual microscopic disease after debulking cytoreductive surgery. During HIPEC, a limited number of catheters are used to administer and drain fluid containing chemotherapy (41-43 °C), yielding heterogeneities in the perito...