Chromatin accessibility dynamics in colorectal cancer liver metastasis: Uncovering the liver tropism at single cell resolution

• Main Authors: Shasha Li (Author), Ming Yang (Author), Shuaishuai Teng (Author), Kequan Lin (Author), Yumei Wang (Author), Yanmei Zhang (Author), Wei Guo (Author), Dong Wang (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor metastasis causes over 90% of cancer related death and no currently available therapies target it. However, there is limited understanding regarding the epigenetic regulation of genes during this complex process. Here by integrating single-cell ATAC-seq (scATAC-seq), single-cell RNA-seq (scRNA...