Dynamic tuft cell expansion during gastric metaplasia and dysplasia

• Main Authors: Bogun Jang (Author), Hyesung Kim (Author), Su‐Hyung Lee (Author), Yoonkyung Won (Author), Izumi Kaji (Author), Robert J Coffey (Author), Eunyoung Choi (Author), James R Goldenring (Author)
• Format: Book
• Published: Wiley, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tuft cells are chemosensory cells associated with luminal homeostasis, immune response, and tumorigenesis in the gastrointestinal tract. We aimed to elucidate alterations in tuft cell populations during gastric atrophy and tumorigenesis in humans with correlative comparison to relevant mous...