Rebamipide does not interfere with the antitumor effect of radiotherapy or chemotherapy in human oral tumor-bearing nude mice

• Main Authors: Masafumi Shibamori (Author), Masayuki Sato (Author), Naoya Uematsu (Author), Takako Nakashima (Author), Asuka Sato (Author), Yoshiya Yamamura (Author), Hiroyuki Sasabe (Author), Ken Umehara (Author), Kazushi Sakurai (Author)
• Format: Book
• Published: Elsevier, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent studies have shown that rebamipide, which suppresses reactive oxygen species, prevents chemoradiotherapy-induced oral mucositis in patients with head and neck cancers. However, anticancer action of radiotherapy and chemotherapy is believed to be partially associated with generation of reactiv...