Activated Protein C Inhibits Proliferation and Tumor Necrosis Factor α-Stimulated Activation of p38, c-Jun NH2-Terminal Kinase (JNK) and Akt in Rheumatoid Synovial Fibroblasts

Abstract Synovial fibroblast proliferation Is a hallmark of the Invasive pannus in the rheumatoid joint. Activated protein C (APC) is a natural anticoagulant that exerts antiinflammatory and cyto-protective effects in various diseases via endothelial protein C receptor (EPCR) and proteinase-activate...

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Main Authors: Sohel M. Julovi (Author), Kaitlin Shen (Author), Kelly McKelvey (Author), Nikita Minhas (Author), Lyn March (Author), Christopher J. Jackson (Author)
Format: Book
Published: BMC, 2013-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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