Association of NPC1L1 and HMGCR gene polymorphisms with coronary artery calcification in patients with premature triple-vessel coronary disease

• Main Authors: Yulong Li (Author), Jiawen Li (Author), Xiaofang Tang (Author), Jingjing Xu (Author), Ru Liu (Author), Lin Jiang (Author), Jian Tian (Author), Yin Zhang (Author), Dong Wang (Author), Kai Sun (Author), Bo Xu (Author), Wei Zhao (Author), Rutai Hui (Author), Runlin Gao (Author), Lei Song (Author), Jinqing Yuan (Author), Xueyan Zhao (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Coronary artery calcification (CAC) is a highly specific marker of atherosclerosis. Niemann-Pick C1-like 1 (NPC1L1) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are the therapeutic targets of ezetimibe and statins, respectively, which are important for the progress...