Activation studies of the α- and β-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with amines and amino acids

• Auteurs principaux: Andrea Angeli (Auteur), Sonia Del Prete (Auteur), Sameh M. Osman (Auteur), Fatmah A. S. Alasmary (Auteur), Zeid AlOthman (Auteur), William A. Donald (Auteur), Clemente Capasso (Auteur), Claudiu T. Supuran (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The α- and β-class carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacterium Vibrio cholerae, VchCAα, and VchCAβ, were investigated for their activation with natural and non-natural amino acids and amines. The most effective VchCAα activators were L-tyrosine, histamine, serotonin, and 4-am...