Retroperitoneal paraganglioma in a patient with Fontan: The hypoxia connection

• Main Authors: Shriprasad R Deshpande (Author), Priyanka Patel (Author), Neill Videlefsky (Author), Dellys M Soler Rodriguez (Author), Rene Romero (Author), Matthew S Clifton (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Paragangliomas are rare neuroendocrine tumors where hypoxia-inducible factor plays a critical role in tumorigenesis. It has been suggested that patients with congenital heart disease, in particular, may have cellular environment and relative hypoxia favorable to the development of these neuroendocri...