The Identification of Long Non-coding RNA H19 Target and Its Function in Chronic Myeloid Leukemia

• Main Authors: Juhua Yang (Author), Zhao Yin (Author), Yumin Li (Author), Yanjun Liu (Author), Guiping Huang (Author), Chunming Gu (Author), Jia Fei (Author)
• Format: Book
• Published: Elsevier, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

H19 is a long non-coding RNA which was lowly expressed in chronic myeloid leukemia (CML). Here, we found that the overexpression of H19 significantly inhibited cell viability and colony formation and prolongs survival in CML cell lines and three xenografted mouse models. The H19 target proteins and...