Alu-repeat polymorphism in the tissue plasminogen activator (t-PA) gene, seminal t-PA concentration, and male fertility impairment: A case-control study

• Main Authors: Lubna Hamid Tahtamouni (Author), Mahmoud Nael Hamdan (Author), Zainab Ali Al-Mazaydeh (Author), Randa Mahmoud Bawadi (Author), Majdoleen Sobhi Rammaha (Author), Ahmad Mohammad Zghoul (Author), Mamoun Ahmad Ahram (Author), Salem Refat Yasin (Author)
• Format: Book
• Published: Shahid Sadoughi University of Medical Sciences, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Tissue plasminogen activator (t-PA) is a protein involved in the fibrinolytic system that catalyzes the conversion of plasminogen into the active plasmin. The activity of t-PA is controlled by plasminogen activator inhibitor-1. t-PA has crucial functions during spermatogenesis. One polym...