Lithium and Neuropsychiatric Therapeutics: Neuroplasticity via Glycogen Synthase Kinase-3β, β-Catenin, and Neurotrophin Cascades

• Autore principale: Akihiko Wada (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2009-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract.: Mood disorders are not merely attributed to the functional defect of neurotransmission, but also are due to the structural impairment of neuroplasticity. Chronic stress decreases neurotrophin levels, precipitating or exacerbating depression; conversely, antidepressants increase expression...