Study of Viral Photoinactivation by UV-C Light and Photosensitizer Using a Pseudotyped Model

• Main Authors: Mohammad Sadraeian (Author), Fabio Francisco Pinto Junior (Author), Marcela Miranda (Author), Juliana Galinskas (Author), Rafaela Sachetto Fernandes (Author), Edgar Ferreira da Cruz (Author), Libing Fu (Author), Le Zhang (Author), Ricardo Sobhie Diaz (Author), Gustavo Cabral-Miranda (Author), Francisco Eduardo Gontijo Guimarães (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Different light-based strategies have been investigated to inactivate viruses. Herein, we developed an HIV-based pseudotyped model of SARS-CoV-2 (SC2) to study the mechanisms of virus inactivation by using two different strategies; photoinactivation (PI) by UV-C light and photodynamic inactivation (...