Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters

• Main Authors: Siennah R. Miller (Author), Joseph L. Jilek (Author), Meghan E. McGrath (Author), Raymond K. Hau (Author), Erin Q. Jennings (Author), James J. Galligan (Author), Stephen H. Wright (Author), Nathan J. Cherrington (Author)
• Format: Book
• Published: Wiley, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Acute lymphoblastic leukemia (ALL) is the most common cancer in children and adolescents. Although the 5‐year survival rate is high, some patients respond poorly to chemotherapy or have recurrence in locations such as the testis. The blood-testis barrier (BTB) can prevent complete eradicati...