From Rate-Limiting Enzyme to Therapeutic Target: The Promise of NAMPT in Neurodegenerative Diseases

From Rate-Limiting Enzyme to Therapeutic Target: The Promise of NAMPT in Neurodegenerative Diseases

Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in the nicotinamide adenine dinucleotide (NAD) salvage pathway in mammals. It is of great significance in the metabolic homeostasis and cell survival via synthesizing nicotinamide mononucleotide (NMN) through enzymatic activi...

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Main Authors: Yumeng Zhu (Author), Ping Xu (Author), Xuan Huang (Author), Wen Shuai (Author), Li Liu (Author), Shuai Zhang (Author), Rui Zhao (Author), Xiuying Hu (Author), Guan Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
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