From Rate-Limiting Enzyme to Therapeutic Target: The Promise of NAMPT in Neurodegenerative Diseases

• Asıl Yazarlar: Yumeng Zhu (Yazar), Ping Xu (Yazar), Xuan Huang (Yazar), Wen Shuai (Yazar), Li Liu (Yazar), Shuai Zhang (Yazar), Rui Zhao (Yazar), Xiuying Hu (Yazar), Guan Wang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in the nicotinamide adenine dinucleotide (NAD) salvage pathway in mammals. It is of great significance in the metabolic homeostasis and cell survival via synthesizing nicotinamide mononucleotide (NMN) through enzymatic activi...