Simulation of the oxidative metabolization pattern of netupitant, an NK1 receptor antagonist, by electrochemistry coupled to mass spectrometry

• Κύριοι συγγραφείς: Ruxandra Chira (Συγγραφέας), Jens Fangmeyer (Συγγραφέας), Ioan O. Neaga (Συγγραφέας), Valentin Zaharia (Συγγραφέας), Uwe Karst (Συγγραφέας), Ede Bodoki (Συγγραφέας), Radu Oprean (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2021-10-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Considering the frequent use of netupitant in polytherapy, the elucidation of its oxidative metabolization pattern is of major importance. However, there is a lack of published research on the redox behavior of this novel neurokinin-1 receptor antagonist. Therefore, this study was performed to simul...