Renal carcinoma/kidney progenitor cell chimera organoid as a novel tumorigenesis gene discovery model

• Główni autorzy: Qi Xu (Autor), Sanna Junttila (Autor), Andreas Scherer (Autor), Khem Raj Giri (Autor), Oona Kivelä (Autor), Ilya Skovorodkin (Autor), Juha Röning (Autor), Susan E. Quaggin (Autor), Hans-Peter Marti (Autor), Jingdong Shan (Autor), Anatoly Samoylenko (Autor), Seppo J. Vainio (Autor)
• Format: Książka
• Wydane: The Company of Biologists, 2017-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Three-dimensional (3D) organoids provide a new way to model various diseases, including cancer. We made use of recently developed kidney-organ-primordia tissue-engineering technologies to create novel renal organoids for cancer gene discovery. We then tested whether our novel assays can be used to e...