5-HT Drives Mortality in Sepsis Induced by Cecal Ligation and Puncture in Mice

• Main Authors: Jingyao Zhang (Author), Jianbin Bi (Author), Sushun Liu (Author), Qing Pang (Author), Ruiyao Zhang (Author), Shun Wang (Author), Chang Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection with a high mortality. 5-Hydroxytryptamine (5-HT) is an important regulatory factor in inflammation. The aim of this study is to investigate the role of 5-HT on cecal ligation and puncture-...