mRNA Expression and Activity of Nucleoside Transporters in Human Hepatoma HepaRG Cells

• Main Authors: Abdullah Mayati (Author), Amélie Moreau (Author), Elodie Jouan (Author), Marie Febvre-James (Author), Claire Denizot (Author), Yannick Parmentier (Author), Olivier Fardel (Author)
• Format: Book
• Published: MDPI AG, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The HepaRG cell line is a highly differentiated human hepatoma cell line, displaying the expression of various drug transporters. However, functional expression of nucleoside transporters remains poorly characterized in HepaRG cells, although these transporters play a key role in hepatic uptake of a...