Quinuclidine-Based Carbamates as Potential CNS Active Compounds

• Main Authors: Ana Matošević (Author), Andreja Radman Kastelic (Author), Ana Mikelić (Author), Antonio Zandona (Author), Maja Katalinić (Author), Ines Primožič (Author), Anita Bosak (Author), Tomica Hrenar (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The treatment of central nervous system (CNS) diseases related to the decrease of neurotransmitter acetylcholine in neurons is based on compounds that prevent or disrupt the action of acetylcholinesterase and butyrylcholinesterase. A series of thirteen quinuclidine carbamates were designed using qui...