Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway

Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway

Abstract Background Methanol extract (MECN) of Clinacanthus nutans Lindau leaves (family Acanthaceae) demonstrated peripherally and centrally mediated antinociceptive activity via the modulation of opioid/NO-mediated, but cGMP-independent pathway. In the present study, MECN was sequentially partitio...

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Main Authors: Zainul Amiruddin Zakaria (Author), Mohammad Hafiz Abdul Rahim (Author), Mohd Hijaz Mohd Sani (Author), Maizatul Hasyima Omar (Author), Siew Mooi Ching (Author), Arifah Abdul Kadir (Author), Qamar Uddin Ahmed (Author)
Format: Book
Published: BMC, 2019-04-01T00:00:00Z.
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