Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway

• المؤلفون الرئيسيون: Zainul Amiruddin Zakaria (مؤلف), Mohammad Hafiz Abdul Rahim (مؤلف), Mohd Hijaz Mohd Sani (مؤلف), Maizatul Hasyima Omar (مؤلف), Siew Mooi Ching (مؤلف), Arifah Abdul Kadir (مؤلف), Qamar Uddin Ahmed (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2019-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Methanol extract (MECN) of Clinacanthus nutans Lindau leaves (family Acanthaceae) demonstrated peripherally and centrally mediated antinociceptive activity via the modulation of opioid/NO-mediated, but cGMP-independent pathway. In the present study, MECN was sequentially partitio...