A tannin compound from Sanguisorba officinalis blocks Wnt/β-catenin signaling pathway and induces apoptosis of colorectal cancer cells

• Main Authors: Wa Li (Author), Chun-juan Yang (Author), Li-qian Wang (Author), Juan Wu (Author), Cong Dai (Author), Yue-mei Yuan (Author), George Q. Li (Author), Mei-cun Yao (Author)
• Format: Book
• Published: BMC, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sanguisorba officinalis, a popular Chinese herb, called DiYu, has been shown to inhibit the growth of many human cancer cell lines, including colorectal cancer cells. The aims of this study were to discover the active compound and molecular mechanism of S. officinalis against Wnt...